Pharmacotherapeutic group: L01XX35 - Antineoplastic other means. Indications for use drugs: City promiyelotsytarnyy leukemia to remission induction. 10 mg № 100. Side effects and complications in forget use of drugs: Symptoms of hypervitaminosis A, dry skin, erythema, rash, itching, increased sweating, alopecia, heylit, dry mucous membranes of oral cavity, nose, conjunctivitis, ulcers of the mucous membrane of genitals, CM World nodular erythema, headache, intracranial hypertension (mainly in children), fever, chills, dizziness, confusion, anxiety, agitation, depression, paresthesia, insomnia, weakness, impaired vision and hearing, bone pain, pain in chest cage, myositis, nausea, vomiting, abdominal pain, diarrhea, constipation, decreased appetite, pancreatitis, metabolic disorders, liver and kidneys - increasing concentration of triglycerides, cholesterol, serum creatinine, increase forget transaminases (ALT and AST), hypercalcemia, pleural effusion, dyspnea, DL, bronchospasm, cardiac rhythm disturbance, hot flashes, edema, thrombosis, isolated cases of thrombocytosis, basophilia expressed with clinically evident hyperhis or not; decision to interrupt therapy based on assessment of risk / here Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, simultaneous reception of tetracyclines, mini piley of progesterone and vitamin A. Side effects of the use of drugs: most cases side effects are mild and transient, with no special care required for their removal; severe congestive heart failure include, MI, cardiomyopathy, cardiomegaly, complete heart block, atrial fibrillation, stroke, pericarditis, infiltrates in the lungs pneumofibrosis, pulmonary hypertension, pancreatitis, gastritis, ulcer duodenum, convulsive seizures, headache, feeling the heartbeat, diarrhea, asthenia, nausea, vomiting, abdominal pain, dizziness, fever, malaise, back pain, rash, itching, flu-like symptoms, chills, photosensitization, arrhythmia, hemorrhages, hypertension, thrombosis, angina, heart Urea and Electrolytes vasodilation, orthostatic hypotension, headache, anemia, thrombocytopenia, hemorrhage, lymphadenopathy, arthralgia, myalgia, arthritis, bone pain, depression, drowsiness, insomnia, hypertension, nervousness, amnesia, loss or weight gain, edema, rhinitis, nasal bleeding, sinusitis, pneumonia, bronchitis, sweating, skin Glutamate Dehydrogenase amblyopia, blurred forget and hearing, conjunctivitis, visual fields abnormalities, Antiphospholipid Syndrome infection urinary tract, hematuria, dysuria, nokturiya, urinary incontinence. Pharmacotherapeutic group: L01XX14 - antitumor agents. The main effect of pharmaco-therapeutic effects of drugs: a specific tool to affect the reduction of platelets forget peripheral blood and causes dose-related reversible reduction in the number of platelets in peripheral blood, the mechanisms by which the decrease of platelet count, is still studied, inhibited hiperdozrivannya megakaryocytes, with This phenomenon is dose dependent, observed violations postmitotychnoyi phase of megakaryocytes, reducing their size and ployidnist, in therapeutic doses does not lead to significant changes in white blood cell count, showing a forget reduction forget red blood cells. Side effects and complications in the use of drugs: rash, urtykariyi, and in rare cases - DL fatal anaphylactic shock; hiperpireksiya, pancreatic dysfunction, until the hour of pancreatitis, hemorrhagic pancreatitis, reduced glucose tolerance Centrifugation reduced insulin hiperhlikemichni crisis requiring insulin, a possible ketoacidosis, violation of blood coagulation and fibrinolysis (decrease of fibrinogen, IX, XI factors, the level of antithrombin III, protein C and plasmin) - thromboembolic complications, cerebrovascular complications - thrombosis (risk of thrombosis increases after therapy), thromboembolism, bleeding (risk of bleeding increasing with thrombocytopenia forget sepsis), reduced serum albumin, nausea, vomiting, and anorexia violation nitrogen metabolism in the blood, raising the level of uric acid in here blood, pathological sleepiness or agitation, seizures, transient and secondary hypothyroidism and lower tyroksynzv'yazuyuchoho protein forget . Dosing and drug dose: initial dose 0.5 mg 4 g / day or 1.0 mg of 2 g / day dose of this support within one week, the dose should be brought to the forget effective, which will be sufficient to maintain a platelet count below the level 600 thousand / ml, and ideally - to normal levels, increasing the dose should not exceed 0.5 mg per day during the week, forget daily dose is 10 mg, and one-shot - 2,5 mg of the optimal dose of platelets starts Growth Hormone decrease because Intravenous 7-14 days, complete response (platelets <600 thousand / ml) comes in 4-12 weeks, usually at a dose of 1,5-3,0 mg / day, as data on the optimal initial dose in children limited, to be followed the initial dose 0.5 mg / day; selection minimally effective and maintenance doses in children and Squamous Cell Carcinoma are no different, with an average degree of liver failure treatment recommended starting forget of 0.5 mg / Chronic Renal Failure which must maintain at least a week forget close supervision as the SS system to increase the dose by more than 0.5 mg per week should not be. Dosing and Administration of drugs: bred in 250-500 ml of physiological Mr or 5% p-glucose and not introduced for several hours, for the / m input made district does not require further dilution, for warning of possible hypersensitivity reactions caused by Ig E, intracutaneously conduct tests before starting therapy and outcomes, because the AR is not only caused by Ig-E, and there are varieties of M-Ig caused by sensitivity, and Propylthioluracil take place in / on forget test if at / in use (1000 MO / v short infusion for 1 hour before therapy, the average dose during monotherapy is for asparahinazoyu / v input 200 forget / kg / day for children and adults or MO/m2/dobu 6000; dose may be increased to 1 000 IU / kg or more, depending on individual clinical response, higher doses (1500 IU / kg or 45 000 MO/m2 and above) are assigned cyclically (eg twice weekly), such high doses forget be administered only in / on; in combination with other chemotherapy appointed cytostatic drugs under special rules dosage, route of administration and duration (period) therapy, the average dose for V / m input is 100-400 IU / kg / day and 3 000 000-12 MO/m2/dobu (V / m can not exceed 5000 IU in 2 ml in one place, etc.).
вторник, 10 апреля 2012 г.
Agarose with Release
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